Isaac Clarke, the hero of the first Dead Space, is having a bad day. After surviving the events of the first game (sorry if revealing that the hero does not die is a spoiler), he finds himself on the densely populated space station known as the Sprawl. You can probably guess what happens next.
Isaac wakes on the Sprawl to find himself in the hospital, suffering from a weird form of dementia. Bad things begin to happen. The Necromorph horde has begun to turn the population of the space station into creepy things, and Isaac is once again thrust into the situation of having to kill everything he finds, in inventive and graphically pleasing ways.
Beyond that, the details are somewhat sparse. The game is due out on January 25, 2011 on PC, Xbox 360, and the PS3. The PS3 will also be offering a port of the Wii-prequel game Dead Space: Extraction, with PlayStation Move support.
More on this game when it comes, but for now enjoy the impressively creepy trailer.
Warning: This trailer may not be suitable for all ages.